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| Related API | Intermediate Name | CAS Number | Structure |
|---|---|---|---|
| 2,3-Difluoro Bromobenzene | Rimegepant | 38573-88-5 |  |
| N3-(piperidin-4-yl)pyridine-2,3-diamine dihydrochloride | Rimegepant | 1373116-08-5 |  |
| 1,3-Dihydro-1-[1-(1H-imidazol-1-ylcarbonyl)-4-piperidinyl]-2H-imidazo[4,5-b]pyridin-2-one | Rimegepant | 1373116-06-3 |  |
| tert-Butyl 4-[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate | Rimegepant | 781649-86-3 |  |
| 2-fluoro-4-nitrobenzoic acid | Enzalutamide/ Apalutamide | 403-24-7 |  |
| 4-Amino-2-Fluoro-N-Methylbenzamide | Enzalutamide/ Apalutamide | 915087-25-1 |  |
| 4-(Methylthio)benzyl cyanide | Etoricoxib | 18991‑39‑4 |  |
| 6-Bromopyrrolo[2,1-f][1,2,4]triazin-4(3H)-one | Avapritinib | 888721-83-3 |  |
| Ilaprazole | 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole | CAS: 172152-53-3 |  |
| Strontium Ranelate, Bispidine | 1,5-Dimethyl 3-oxopentanedioate | CAS: 1830-54-2 |  |
Osimertinib |
1-(1-Methyl-1H-indol-3-yl)ethanone | CAS:19012-02-3 |  |
| Osimertinib | 3-(2-Chloro-4-pyrimidi nyl)-1-methyl-1H-indole | CAS: 1032452-86-0 |  |
| Osimertinib | N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine | CAS: 1421372-94-2 |  |
| Osimertinib | 4-Fluoro-2-methoxy-5-nitrobenzenamine | CAS:1075705-01-9 |  |
| Remdesivir | 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone | CAS:55094-52-5 |  |
| Remdesivir | 1-Amino-1H-pyrrole-2-carbonitrile | CAS: 159326-66-6 |  |
| Remdesivir | Pyrrolo[2,1-f][1,2,4] triazin-4-amine |
CAS: 159326-68-8 |  |
| Remdesivir | 4-Amino-7-iodo-pyrrolo[2,1-f][1,2,4] triazine | CAS:1770840-43-1 |  |
| Finerenone Sunitinib | 2,2,6-Trimethyl4-1-3-Dioxin-4-One |
CAS:5394-63-8 |  |
| Finerenone | 2-Chloro-5-methyl pyridine-4-yl amine | CAS: 79055-62-2 |  |
| Diazo transfer reagent | 4-Acetamidobenzenes ulfonyl azide |
CAS: 2158-14-7 |  |
Donepezil |
1-(Phenylmethyl)-4-piperidinecarboxaldehyde | CAS: 22065-85-6 |  |
Donepezil |
5,6-Dimethoxy-1-indanone | CAS: 2107-69-9 |  |
| Voxelotor | Pyridine, 3-(chloromethyl)-2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-, dihydrochloride | CAS:2152677-40-0 (2HCl) |  |
| Voxelotor | 1-(1-Methylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | CAS: 1282518-60-8 |  |
| Voxelotor | 2-[1-(1-Methylethyl)-1H-pyrazol-5-yl]-3-pyridinemethanol | CAS: 1446321-93-2 |  |
| Cudetaxestat | 4-Bromo-1-propyl-1H-pyrazole |
CAS: 141302-33-2 |  |
| Cudetaxestat | 6-Chloro-7-fluoro Indole | CAS: 259860-04-3 |  |
| Crizotinib | 1,1-Dimethylethyl 4-bromo-1H-pyrazole-1-carboxylate | CAS: 1150271-23-0 |  |
| Crizotinib | tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine. | CAS: 877399-74-1 |  |
| Crizotinib | 1-Piperidinecarboxylic acid, 4-(4-bromo-1H-pyrazol-1-yl)-, phenylmethyl ester | CAS: 2680701-05-5 |  |
| Crizotinib | tert-Butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate | CAS: 877399-73-0 |  |
| Crizotinib | 1,1-Dimethylethyl 4-(4-bromo-1H-pyrazol-1-yl)-1-piperidine carboxylate | CAS: 877399-50-3 |  |
| Crizotinib | 2-Amino-5-bromo-3-hydroxypyridine | CAS: 39903-01-0 |
 |
| Darolutamide | 3-Acetyl-1H-pyrazole-5-carboxylic acid | CAS: 1297537-45-1 |  |
| Chloroquine, Hydroxy Chloroquine | 4,7-Dichloroquinoline | CAS: 86-98-6 |  |
| BL001 | (E)-4-(3-methoxyphenyl)-5-(oct-4-en-4-yl)-N-phenyl-1,2,3,3a,6,6a-hexahydropentalen-3a-amine | CAS: 916817-62-4 |  |
| Nemonoxacin | 1-Cyclopropyl-7-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | CAS: 221221-16-5 |  |
| Nemonoxacin | 2,6-difluoro anisole | CAS:437-82-1 |  |
| Nemonoxacin | 1,1-Dimethylethyl N-[(3S,5S)-5-methyl-3-piperidinyl]carbamate | CAS:951163-61-4 CAS:1229616-30-1 (Oxalate salt) |
 |
| Xofluza,Baloxavir | 7,8-Difluoro-6,11-dihydro dibenzo-[b,e]thiepin-11-ol | CAS: 1985607-83-7 |  |
| Xofluza,Baloxavir | 7,8-ifluorodibenzo[b,e]thiepin-11(6H)-one | CAS:2136287-66-4 |  |
| Galunisertib | 4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinoline | CAS: 924898-13-5 |  |
| Galunisertib | 6-Quinolinecarboxamide, 4-[5,6-dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]- (9CI, ACI) | CAS: 700874-72-2 |  |
| Galunisertib | 4-Methyl-6-quinolinecarbonitrile | CAS:924962-08-3 |  |
| Galunisertib | 2-Pyridinecarboxylic acid, 6-methyl-, methyl ester | CAS: 13602-11-4 |  |
| Galunisertib | 2-Pyrrolidinone, 1-amino-, 4-methylbenzene sulfonate (1:1) | CAS: 924898-12-4 |  |
| Cabozatinib | 4-Chloro-6,7-dimethoxyquinoline | CAS:35654-56-9 |  |
| Cabozatinib | N-(4-Fluorophenyl)-N′-(4-hydroxyphenyl)-1,1-cyclopropanedicarboxamide | CAS:849217-60-3 |  |
| Sitravatinib | 3-Pyridinemethanamine, 6-(7-chlorothieno[3,2-b]pyridin-2-yl)-N-(2-methoxyethyl)- | CAS:2752171-14-3 |  |
| Sitravatinib | 7-Chlorothieno[3,2-b]pyridine | CAS:69627-03-8 |  |
| Sitravatinib | 6-Bromo-N-(2-methoxyethyl)-3-pyridinemethanamine | CAS:1123837-99-9 |  |
| Sitravatinib | 6-Bromo-3-pyridine carboxaldehyde | CAS:149806-06-4 |  |
| Ribociclib Palbociclib | tert-Butyl 4-(6-amino pyridin-3-yl)pipera zine-1-carboxylate | CAS:571188-59-5 |  |
| Palbociclib | 6-Acetyl-8-cyclopentyl-5-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one |
CAS: 850628-81-8 |
 |
| For New NCEs | 3-Benzyl-3,9-diaza spiro[5.5]undecane dihydrochloride | CAS: 1171506-89-0 |  |
| Ruxolitinib, Baricitinib, Abrocitinib | 7-Deazahypoxanthine | CAS: 3680-71-5 |  |
| Ruxolitinib, Baricitinib, Abrocitinib | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | CAS: 3680-69-1 |  |
| Ruxolitinib, Baricitinib | 4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine | CAS: 952518-97-7 |  |
| Cilostazol | 5-(4-Chlorobutyl)-1-cyclohexyl-1H-tetrazole | CAS: 73963-42-5 |  |
| Cilostazol | 6-Hydroxy-3,4-dihydro-2(1H)-quinolinone | CAS: 54197-66-9 |
 |
| Linezolid | 3-Fluoro-4-morpholinoaniline | CAS: 93246-53-8 |  |
| Linezolid | 4-(2-Fluoro-4-nitrophenyl)morpholine | CAS:2689-39-6 |
 |
| Bempedoic Acid | Bempedoic acid |
CAS: 738606-46-7 |
 |
| Etoricoxib | Methyl 6-methylnicotinate |
CAS: 5470-70-2 |
 |
| Etoricoxib | 1-(6-Methyl-3-pyridinyl)ethanone |
CAS: 36357-38-7 |
 |
| Etoricoxib | 4-(Methylsulfonyl)phenylacetic acid |
CAS: 90536-66-6 |
 |
| Etoricoxib | 1-(6-Methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone |
CAS: 22165-75-4 |
 |
| For New NCE | 2-(4-Sulfamoylphenyl) acetic acid | CAS: 22958-64-1 |  |
| General Building block | Ethyl isocyano acetate | CAS: 2999-46-4 |  |
| Reagent | 2-(Triphenylphosphora nylidene)acetaldehyde | CAS: 2136-75-6 |  |
| General Building block | 2-Bromo-3-chloro aniline | CAS: 96558-73-5 |  |
| General Building block | Dicyclopropyl ketone | CAS:1121-37-5 |  |
| Protaglandins | Cis-icyclo[3.3.0]octane- 3,7-dione | CAS: 51716-63-3 |  |
| NCE Fragment | 2-(Trifluoromethyl)-5-thiazolemethanamine | CAS: 1393534-24-1 |  |
| Ligand | 2-[2-(Dicyclohexylphos phino) phenyl]-1-methyl-1H-indole | CAS: 1067883-58-2 |  |